Study reveals potential role of microglia in TBI cases

A new study conducted by researchers at the University of Virginia School of Medicine may be of interest to anyone in West Virginia who has suffered a traumatic brain injury or spinal cord injury. Researchers discovered that microglia, which are certain cells that reside permanently in the central nervous system, have an important role in clearing up dead and dying cells in the brain.

In an experiment, these phagocytic cells (so called because they literally eat other cells) were found in the brains of mice with injured optic nerves. The retinal ganglion neurons had degenerated and left the brain with debris, which was being consumed by the microglia. Removing dead and dying cells is crucial because if left alone, they can become inflamed and affect neighboring neurons.

Microglia have other beneficial roles. They aid in the development of the brain by "pruning" inactive neuronal synapses, and they fight brain infections by eating away the bacteria and other pathogens. In adult brains, microglia can recognize dead or injured neurons, inactive synapses and bacteria using similar molecules.

While the study was limited to optic nerve injuries in mice, researchers believe that further research into the way that microglia are activated following a TBI or spinal cord injury will be fruitful. Ultimately, it could help limit the spread of neurodegeneration in patients.

TBIs can be hard to detect, and the extent of the damage they cause can be hard to measure. Victims could, for example, suffer from delayed brain damage. Whatever the nature of the accident, victims who were injured through no fault of their own may qualify for compensation under personal injury law. They might decide to hire a lawyer, who may, in turn, hire medical professionals to link the accident with the symptoms. The lawyer might then negotiate for a settlement covering past and future medical expenses.

No Comments

Leave a comment
Comment Information

Tell Us About Your Legal Issue

Bold labels are required.

Contact Information

The use of the Internet or this form for communication with the firm or any individual member of the firm does not establish an attorney-client relationship. Confidential or time-sensitive information should not be sent through this form.


Privacy Policy

This site uses Google's Invisible reCAPTCHA, which is subject to Google's Privacy Policy and Terms of Use.

Email Us For A Response

Three Convenient Office Locations

Charleston Office
746 Myrtle Rd
Charleston, WV 25314

Toll Free: 866-587-0167
Toll Free: 866-587-0167
Phone: 304-881-0637
Phone: 304-881-0637
Charleston Law Office Map

Beckley Office
101 N. Kanawha St
Suite 101
Beckley, WV 25801

Toll Free: 866-587-0167
Toll Free: 866-587-0167
Phone: 304-881-0637
Phone: 304-881-0637
Beckley Law Office Map

Morgantown Office
453 Suncrest Towne Centre Drive
Suite 300
Morgantown, WV 26505

Toll Free: 866-587-0167
Toll Free: 866-587-0167
Phone: 304-881-0637
Phone: 304-881-0637
Morgantown Law Office Map

Get Answers Today
Get The Answers You Need And The Advice You Deserve